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1

Cancer biomarkers: selecting the right drug for the right patient

Kelloff, Gary J., Sigman, Caroline C.

Journal:

Nature Reviews Drug Discovery

Année:

2012

Langue:

english

Fichier:

PDF, 528 KB

english, 2012

2

What evidence do we need for biomarker qualification?

Leptak, Chris, Menetski, Joseph P., Wagner, John A., Aubrecht, Jiri, Brady, Linda, Brumfield, Martha, Chin, William W., Hoffmann, Steve, Kelloff, Gary, Lavezzari, Gabriela, Ranganathan, Rajesh, Sauer,

Journal:

Science Translational Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 213 KB

english, 2017

3

Overview of precancer and goals of the meeting

Kelloff, Gary J., Kelloff, G.J.

Journal:

Cancer Biomarkers

Année:

2006

Langue:

english

Fichier:

PDF, 7 KB

english, 2006

4

Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model

Ronald A. Lubet, Vernon E. Steele, Isao Eto, M. Margaret Juliana, Gary J. Kelloff, Clinton J. Grubbs

Journal:

International Journal of Cancer

Année:

1997

Langue:

english

Fichier:

PDF, 210 KB

english, 1997

5

Risk biomarkers and current strategies for cancer chemoprevention

Gary J. Kelloff, Charles W. Boone, James A. Crowell, Susan G. Nayfield, Ernest Hawk, Winfred F. Malone, Vernon E. Steele, Ronald A. Lubet, Caroline C. Sigman

Journal:

Journal of Cellular Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 1.28 MB

english, 1996

6

Inherited susceptibility and acquired allelic imbalance in rat mammary carcinogenesis

Michael N. Gould, Ronald A. Lubet, Gary J. Kelloff, Jill D. Haag

Journal:

Journal of Cellular Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 436 KB

english, 1996

7

DNA quantification in cervical intraepithelial neoplasia thick tissue sections by confocal laser scanning microscopy

Keith A. Crist, Kitai Kim, Peter J. Goldblatt, Charles W. Boone, Gary, J. Kelloff, Ming You

Journal:

Journal of Cellular Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 693 KB

english, 1996

8

Detection of genomic alterations in human cervical cancer by two-dimensional gel electrophoresis

Jiafan Liu, Yian Wang, Ping Gu, James Patrick, Keith A. Crist, Carol L.K. Sabourin, Gary D. Stoner, Michele F. Mitchell, James D. Fanning, Kitai Kim, Peter J. Goldblatt, Gary J. Kelloff, Charles W. Bo

Journal:

Journal of Cellular Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 796 KB

english, 1996

9

Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung

Laura E. Lantry, Zhongqiu Zhang, Feng Gao, Keith A. Crist, Yian Wang, Gary J. Kelloff, Ronald A. Lubet, Ming You

Journal:

Journal of Cellular Biochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 72 KB

english, 1997

10

Properties of intraepithelial neoplasia relevant to the development of cancer chemopreventive agents

Boone, Charles W., Bacus, James W., Bacus, James V., Steele, Vernon E., Kelloff, Gary J.

Journal:

Journal of Cellular Biochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 455 KB

english, 1997

11

Effect of early vs. late administration of 4-Hydroxyphenylretinamide (4-HPR) on N-Methyl-N-Nitrosourea (MNU)-induced mammary tumorigenesis

Keith A. Crist, Yian Wang, Ronald A. Lubet, Vernon E. Steele, Gary J. Kelloff, Ming You

Journal:

Journal of Cellular Biochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 83 KB

english, 1997

12

Detection of differentially expressed genes in Methylnitrosourea-induced rat mammary adenocarcinomas

Hu, Lan, Lin, Lin, Crist, Keith A., Kelloff, Gary J., Steele, Vernon E., Lubet, Ronald A., You, Ming, Wang, Yian

Journal:

Journal of Cellular Biochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 187 KB

english, 1997

13

Quantitation of preinvasive neoplastic progression in animal models of chemical carcinogenesis

Bacus, James W., Bacus, James V., Stoner, Gary D., Moon, Richard C., Kelloff, Gary J., Boone, Charles W.

Journal:

Journal of Cellular Biochemistry

Année:

1997

Langue:

english

Fichier:

PDF, 497 KB

english, 1997

14

Clinical development of estrogen modulators for breast cancer chemoprevention in premenopausal vs. postmenopausal women

Julia A. Lawrence, Phyllis B. Malpas, Caroline C. Sigman, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

2000

Langue:

english

Fichier:

PDF, 103 KB

english, 2000

15

Endpoint markers for cancer chemoprevention trials derived from the lesion of precancer (intraepithelial neoplasia) measured by computer-assisted quantitative image analysis

Charles W. Boone, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

2000

Langue:

english

Fichier:

PDF, 312 KB

english, 2000

16

A comparative analysis of allelic imbalance events in chemically induced rat mammary, colon, and bladder tumors

Jill D. Haag, Gerlyn M. Brasic, Laurie A. Shepel, Michael A. Newton, Clinton J. Grubbs, Ronald A. Lubet, Gary J. Kelloff, Michael N. Gould

Journal:

Molecular Carcinogenesis

Année:

1999

Langue:

english

Fichier:

PDF, 123 KB

english, 1999

17

Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light–induced skin carcinogenesis

Susan M. Fischer, Herng-Hsang Lo, Gary B. Gordon, Karen Seibert, Gary Kelloff, Ronald A. Lubet, Claudio J. Conti

Journal:

Molecular Carcinogenesis

Année:

1999

Langue:

english

Fichier:

PDF, 289 KB

english, 1999

18

Chemoprevention of bladder cancer

Winfred F. Malone, Gary J. Kelloff, Herbert Pierson, Peter Greenwald

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 780 KB

english, 1987

19

Concepts in cancer chemoprevention research

Peter Greenwald, Daniel W. Nixon, Winfred F. Malone, Gary J. Kelloff, Harriet R. Stern, Karen M. Witkin

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 913 KB

english, 1990

20

Variations in sarcoma and leukemia virus activity in somatic cell hybrids

Cedric Long, Gary Kelloff, Raymond V. Gilden

Journal:

International Journal of Cancer

Année:

1972

Langue:

english

Fichier:

PDF, 615 KB

english, 1972

21

Type-C virus structural antigens on the surface of the infected cell as determined by a humoral cytotoxicity assay

Meir Kende, Bernard Sass, Shigeo Hino, Robert M. Donahoe, Gary J. Kelloff

Journal:

International Journal of Cancer

Année:

1978

Langue:

english

Fichier:

PDF, 942 KB

english, 1978

22

Naturally occurring humoral immunity to endogenous xenotropic and amphotropic type-C virus in the mouse

Meir Kende, Fulvia Veronese, Dick W. Hill, Marshall Dinowitz, Gary J. Kelloff

Journal:

International Journal of Cancer

Année:

1981

Langue:

english

Fichier:

PDF, 718 KB

english, 1981

23

Monoclonal antibodies to feline sarcoma virus gag and fes gene translational products

Fulvia Veronese, Gary J. Kelloff, Fred H. Reynolds Jr., Richard W. Hill, John R. Stephenson

Journal:

Journal of Cellular Biochemistry

Année:

1983

Langue:

english

Fichier:

PDF, 702 KB

english, 1983

24

The natural history of intraepithelial neoplasia: Relevance to the search for intermediate endpoint biomarkers

Charles W. Boone, Gary J. Kelloff, Vernon E. Steele

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 392 KB

english, 1992

25

Intermediate biomarkers of precancer and their application in chemoprevention

Gary J. Kelloff, Winfred F. Malone, Charles W. Boone, Vernon E. Steele, Linda A. Doody

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 563 KB

english, 1992

26

Growth kinetics and chemoprevention of aberrant crypts in the rat colon

Michael J. Wargovich, Charles Harris, Chi-Dai Chen, Cynthia Palmer, Vernon E. Steele, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 329 KB

english, 1992

27

Introductory remarks: Development of chemopreventive agents for prostate cancer

Gary J. Kelloff, Charles W. Boone, Winfred F. Malone, Vernon E. Steele, Linda A. Doody

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 699 KB

english, 1992

28

Chemoprevention of prostate cancer: Guidelines for possible intervention strategies

E. David Crawford, William R. Fair, Gary J. Kelloff, Michael M. Lieber, Gary J. Miller, Peter T. Scardino, Edward P. DeAntoni

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 635 KB

english, 1992

29

Development of chemopreventive agents for bladder cancer

Gary J. Kelloff, Charles W. Boone, Winfred F. Malone, Vernon E. Steele, Linda A. Doody

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 943 KB

english, 1992

30

Intermediate endpoint biomarkers for chemoprevention

George P. Hemstreet III, Jian Yu Rao, Robert E. Hurst, Rebecca Bass Bonner, Phillip L. Jones, Abhay M. Vaidya, Yves Fradet, Richard C. Moon, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 1.27 MB

english, 1992

31

Chemoprevention of exprimental bladder cancer

Richard C. Moon, Carol J. Detrisac, Cathy F. Thomas, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 465 KB

english, 1992

32

Intraepithelial neoplasia, surrogate endpoint biomarkers, and cancer chemoprevention

Dr. Charles W. Boone, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 930 KB

english, 1993

33

Development of chemopreventive agents for lung and upper aerodigestive tract cancers

Gary J. Kelloff, Charles W. Boone, Vernon K. Steele, Marjorie Perloff, James Crowell, Linda A. Doody

Journal:

Journal of Cellular Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 1.26 MB

english, 1993

34

Intraepithelial and postinvasive neoplasia as a stochastic continuum of clonal evolution, and its relationship to mechanisms of chemopreventive drug action

Charles W. Boone, Gary J. Kelloff, Lawrence S. Freedman

Journal:

Journal of Cellular Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1993

35

Development of breast cancer chemopreventive drugs

Gary J. Kelloff, Charles W. Boone, Vernon E. Steele, James A. Crowell, Ron Lubet, Linda A. Doody, Peter Greenwald

Journal:

Journal of Cellular Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1993

36

Breast cancer chemoprevention clinical trials

Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 106 KB

english, 1993

37

Selection criteria for breast cancer chemoprevention subjects

Mack T. Ruffin, David A. August, Gary J. Kelloff, Charles W. Boone, Barbara L. Weber, Dean E. Brenner

Journal:

Journal of Cellular Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 880 KB

english, 1993

38

Chemoprevention of rat mammary carcinogenesis: Exceptional activity of dietary dehydroepiandrosterone (DHEA)

David L. McCormick, William D. Johnson, Kandala V. N. Rao, Teresa Bowman-Gram, Richard C. Moon, Vernon E. Steele, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 174 KB

english, 1993

39

Mechanistic considerations in chemopreventive drug development

Dr. Gary J. Kelloff, Charles W. Boone, Vernon E. Steele, Judith R. Fay, Ronald A. Lubet, James A. Crowell, Caroline C. Sigman

Journal:

Journal of Cellular Biochemistry

Année:

1994

Langue:

english

Fichier:

PDF, 2.39 MB

english, 1994

40

Strategy and planning for chemopreventive drug development: Clinical development plans

Gary J. Kelloff, James A. Crowell, Charles W. Boone, Vernon E. Steele, Ronald A. Lubet, Peter Greenwald, David S. Alberts, Joseph M. Covey, Linda A. Doody, Gene G. Knapp, Susan Nayfield, David R. Park

Journal:

Journal of Cellular Biochemistry

Année:

1994

Langue:

english

Fichier:

PDF, 804 KB

english, 1994

41

Guidance for development of chemopreventive agents

Gary J. Kelloff, John R. Johnson, James A. Crowell, Charles W. Boone, Joseph J. DeGeorge, Vernon E. Steele, Menul U. Mehta, Jean W. Temeck, Wendelyn J. Schmidt, Gregory Burke, Peter Greenwald, Robert

Journal:

Journal of Cellular Biochemistry

Année:

1994

Langue:

english

Fichier:

PDF, 381 KB

english, 1994

42

Effects of oltipraz and related chemoprevention compounds on gene expression in rat liver

Leigh Anderson, Vernon K. Steele, Gary J. Kelloff, Sheela Sharma

Journal:

Journal of Cellular Biochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 639 KB

english, 1995

43

Strategies for phase II cancer chemoprevention trials: Cervix, endometrium, and ovary

Dr. Gary J. Kelloff, Charles W. Boone, James A. Crowell, Susan G. Nayfield, Ernest Hawk, Vernon E. Steele, Ronald A. Lubet, Caroline C. Sigman

Journal:

Journal of Cellular Biochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 782 KB

english, 1995

44

Use of in vitro assays to predict the efficacy of chemopreventive agents in whole animals

Dr. Vernon E. Steele, Sheela Sharma, Rajendra Mehta, Eugene Elmore, J. Leslie Redpath, Colette Rudd, Donya Bagheri, Caroline C. Sigman, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 1.46 MB

english, 1996

45

Strategy and planning for chemopreventive drug development: Clinical development plans II

Gary J. Kelloff, James A. Crowell, Ernest T. Hawk, Vernon E. Steele, Ronald A. Lubet, Charles W. Boone, Joseph M. Covey, Linda A. Doody, Gilbert S. Omenn, Peter Greenwald, Waun K. Hong, David R. Parki

Journal:

Journal of Cellular Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1996

46

Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas

Christopher R. Herzog, Keith A. Crist, Carol L. K. Sabourin, Gary J. Kelloff, Charles W. Boone, Gary D. Stoner, Ming You

Journal:

Molecular Carcinogenesis

Année:

2001

Langue:

english

Fichier:

PDF, 235 KB

english, 2001

47

Biomarkers of Premalignant Breast Disease and Their Use as Surrogate Endpoints in Clinical Trials of Chemopreventive Agents

Charles W. Boone, Gary J. Kelloff

Journal:

The Breast Journal

Année:

1995

Langue:

english

Fichier:

PDF, 1.62 MB

english, 1995

48

Development of Breast Cancer Chemopreventive Drugs

Gary J. Kelloff, Charles W. Boone, James A. Crowell, Susan G. Nayfield, Ernest Hawk, Vernon E. Steele, Ronald A. Lubet, Caroline C. Sigman

Journal:

The Breast Journal

Année:

1995

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1995

49

Progress in Cancer Chemoprevention

GARY J. KELLOFF, JAMES A. CROWELL, VERNON E. STEELE, RONALD A. LUBET, CHARLES W. BOONE, WINFRED A. MALONE, ERNEST T. HAWK, RONALD LIEBERMAN, JULIA A. LAWRENCE, LEVY KOPELOVICH, IQBAL ALI, JAYE L. VINE

Journal:

Annals of the New York Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 227 KB

english, 1999

50

Replication of Murine and Feline RNA-containing C-type Viruses in Human Lymphoblastoid Cells

OROSZLAN, STEPHEN, GILDEN, RAYMOND V., WALKER, JOHN L., HAMPAR, BERGE, KELLOFF, GARY J., MARTOS, LIDIA M.

Journal:

Année:

1970

Fichier:

PDF, 652 KB

1970